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Symbol
Name
ID
Sh2b1
SH2B adaptor protein 1
MGI:1201407
Phenotype annotations related to endocrine/exocrine glands
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
increased pancreatic beta cell proliferation
endocrine/exocrine gland phenotype
decreased pancreatic beta cell mass
pancreatic islet hyperplasia
small pancreatic islets
increased secondary ovarian follicle number
absent tertiary ovarian follicles
abnormal ovarian folliculogenesis
decreased ovary weight
ovary hypoplasia
decreased Leydig cell number
decreased testis weight
testis hypoplasia
abnormal pancreatic beta cell physiology
decreased insulin secretion
Availability Mouse Genotype
Sh2b1tm1Ayos/Sh2b1tm1Ayos *
Sh2b1tm1Lr/Sh2b1tm1Lr
Sh2b1tm2.1Lr/Sh2b1tm2.1Lr
Tg(Pdx1-cre)89.1Dam/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory